What effective treatment method does allergic purpura have?
therapeutic method
In the acute phase, you should stay in bed and look for allergic factors. For suspicious foods or drugs, stop using them temporarily, or start using them in small quantities under close observation. If it doesn't work, gradually increase the amount and variety of food.
Traditional Chinese medicine therapy
According to the clinical symptoms of the disease.
Western medicine treatment
Commonly used western medicine
1, antiallergic drugs: cisplatin, chlorpheniramine, calcium gluconate.
Drugs for reducing vascular permeability: Luo 'an blood, rutin and vitamin C.
3. Platelet aggregation inhibitor: dipyridamole
4, adrenocortical hormones: hydrocortisone, prednisone (prednisone), dexamethasone.
5. Immunosuppressants (such as cyclophosphamide, azathioprine and other chemotherapy drugs) are also used for patients with renal failure or prednisone treatment.
Adrenal cortical hormone therapy
Adrenal cortical hormone is effective for some children and can improve symptoms. It is effective for abdominal pain with bloody stool and joint symptoms, but it cannot prevent recurrence. It is often ineffective for nephritis and unnecessary for patients with simple skin purpura. Prednisone 1 ~ 2mg/kg/ day is often taken orally in batches, and the symptoms gradually decrease until the drug is stopped after remission. The course of treatment is usually 1 ~ 2 weeks. Patients with severe abdominal pain, hematochezia or cerebral hemorrhage can be given hydrocortisone 150 ~ 300mg/ day (5 ~ 10mg/kg/ day) or dexamethasone 15 ~ 30mg/ day. Renal involvement indicates nephrotic syndrome.
allopathy
1. Aspirin can be used for patients with joint swelling and pain (see section on rheumatic fever).
2, abdominal pain can be calm, such as Lumina. At the same time, observe the signs of abdominal intussusception
3. For patients with gastrointestinal bleeding, limit diet when the amount is small, and fast when the amount is large. You can also use procaine (allergic test first, choose negative) to seal the vein. Add 200ml 15mg/kg/ day for intravenous drip for 7 ~ 10 days.
4, infected people, especially streptococcus infection, can use antibiotics such as penicillin to control infection.
5, there are intestinal parasites, be sure to wait until the gastrointestinal bleeding stops before expelling insects.
6, there are lesions, such as dental caries, sinusitis, tonsillitis and so on. It should be treated thoroughly.
7. Generally, vitamin C, P or calcium can be supplemented.
8, bleeding, anemia can be blood transfusion.
Therapeutic experience
The traditional treatment of henoch-schonlein purpura is symptomatic treatment and application of adrenocortical hormone, but the use of hormone will make the immune system more disordered, with many side effects after long-term use, which is easy to relapse and difficult to stop taking drugs. After 1980, anisodamine was used as the main therapeutic drug for allergic purpura, and good results were obtained. After that, compound glycyrrhizin is superior to corticosteroids in relieving symptoms, shortening the course of disease and recurrence after cure. This article introduces it for your reference:
Basic treatment (routine treatment after admission)
Anisodamine (654-2) can improve microcirculation and restore microvascular autonomic movement.
Reduce exudation, regulate immunity and improve allergic inflammation.
Usage: 250 ml of 5% glucose plus anisodamine 20 ~ 1.20 mg 1 ~ 2 times a day, the dose is proportional to the condition (the most suitable dose is the patient's slightly blurred vision, dry mouth, etc.). )
Compound glycyrrhizin has anti-allergic, anti-inflammatory, anti-virus, immunomodulation and free radical scavenging effects.
Usage: 300 ml of 5% glucose is used to strengthen the lining 5 ~ 8 tablets/day.
Symptomatic treatment
Renal damage: the first onset can be recovered by basic treatment, and repeated use of hormones can increase (decrease) the amount of basic treatment. For example, anisodamine can be given intravenously twice a day, and tripterygium wilfordii can also be added.
Abdominal pain: general basic treatment can be controlled. Severe cases (stool occult blood positive, bleeding, etc. ), cimetidine warm saline enema 1 ~ 2/ day, VK 1 injection, etc. Joint pain: abnormal heart function, basic treatment will soon recover.
Mental nervous system: If the child is sleepy and unconscious, there may be intracranial vasculitis or bleeding, which is a warning signal of danger. If there is a death case that fails to be rescued, it is necessary to cooperate with dehydration in time.
It can also be treated with combination of traditional Chinese and western medicine according to the patient's condition, with western medicine to stabilize acute symptoms and Chinese medicine to regulate. The general treatment time is about half a year, during which the focus should be on preventing recurrence.
physiatrics
Many patients with henoch-schonlein purpura will have obvious erythema, petechiae and other lesions on their skin. If the drug is used alone during the treatment, it will take a long time to get a good therapeutic effect. If the physical method can be used, it can accelerate the skin symptoms of patients, and it is a good auxiliary treatment method. It should be noted that some patients' physique is not suitable for physical therapy, so patients should ask their attending doctors when choosing, and then treat them after confirmation.
Chinese herbal fumigation therapy:
Fumigation therapy of traditional Chinese medicine has therapeutic effect on the body through the effects of temperature, machinery and drugs. Due to warm stimulation, the blood vessels of the skin and the affected area dilate, promote local and systemic blood circulation and lymphatic circulation, have vigorous metabolism, improve local tissue nutrition and systemic function, and promote the regulating function of meridians by dredging meridians, regulating qi and blood; Through drug compatibility, some drugs can be absorbed into the body through the skin, and the other drugs can be attached to the skin to play a role. At the same time, the nerve endings of the skin are stimulated by the nervous system to form new reflexes, thus destroying the original pathological reflex connection and achieving the purpose of curing diseases.