What are the functions and effects of amic acid?

Nicotinamide has many functions, and is often used in cosmetics with whitening, freckle removing, anti-wrinkle and moisturizing, and also has application prospects in the treatment of atopic dermatitis and acne.

Nicotinamide can reduce skin pigmentation. Nicotinamide can play a role in the process of melanin precipitation, preventing melanin from precipitating from melanocytes to keratinocytes. Studies have shown that nicotinamide can effectively reduce melanin precipitation, promote pigmentation and improve skin condition. In a randomized double-blind study, researchers found that nicotinamide can reduce facial pigmentation.

Extended data

Although most studies show that cosmetics containing nicotinamide are safe to use, some consumers will become red, swollen, allergic and itchy after using them. In the comparative test of nicotinamide gel and clindamycin gel, some subjects who used nicotinamide had slight adverse reactions such as itching and burning.

In order to avoid this situation, consumers are advised to try nicotinamide cosmetics on the inside of their arms or behind their ears before using them, and then use them on their faces, so as to avoid redness or tingling. According to a number of test results, the expert group of the American Cosmetic Raw Materials Review Committee concluded that the use of 3% nicotinamide in cosmetics has no obvious irritation, sensitization and photosensitivity to the skin, and nicotinamide itself has no carcinogenic effect, so it is generally considered that it can be used for a long time.

The side effects of skin care products containing nicotinamide mainly come from nicotinic acid, a by-product contained in nicotinamide. Nicotinic acid is irritating to some extent. People who are intolerant may feel slight burning or itching after using products containing nicotinamide, especially those with sensitive skin.

People's Daily Online-Cosmetics containing nicotinamide are not suitable for everyone.