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How should "cold urticaria" be treated in life?

Some people initially thought that cold measles was a common allergy and took a lot of allergy medicines, but they didn’t work. This disease is the most common type of physical urticaria and can occur at any age.

There are two types: familial and acquired. The former is a family inheritance, mainly autosomal dominant gene inheritance, which can occur after birth or early in life and last a lifetime. The latter is more common in young women.

Red dots and bumps appear when exposed to cold, and they are very large. The bumps will appear on any exposed skin. At first, there are no bumps on the face. They usually disappear within two hours after getting up in the morning. Sometimes they are extremely itchy, and the patient It will feel very uncomfortable, but it will be even worse if you scratch it with your hands. Severe cases may also cause edema and even abdominal pain in the mucous membranes of the mouth, tongue, pharynx, etc. when exposed to cold food or drinks.

In the treatment of this disease, the symptoms will sometimes be relieved after injection, but the symptoms will relapse within a few days after each injection. Moreover, when there is a temperature difference between morning and evening, pimples will appear again in the evening when the weather is cooler. Therefore, this treatment method can only relieve symptoms but cannot cure the disease.

Some patients have also tried to eat scorpions directly after deep-frying them according to the dietary therapy method. They also eat warm and tonic food in winter, eat four or five dates after lunch, and wear cotton clothes in winter. Pants protect the thighs and calves, so as to at least try to avoid the incidence of this disease and prevent it from getting worse after the onset.

What are the reasonable treatments for this disease specifically?

1. Treatment can be based on the cause. If there is an infection, antibiotics should be used. Try to avoid eating certain cold foods in your daily life. Cold urticaria is characterized by recurrence, especially if the disease is inherited in families.

2. Although antihistamine drugs cannot directly antagonize or neutralize histamine and cannot prevent the release of histamine, they can compete for histamine and quickly inhibit the formation of wheals. What I want to say is that antihistamines have many side effects, so this drug is not the first choice. When choosing drugs, try to choose drugs with fewer side effects. Antihistamines are also very effective, so sometimes they can be used interchangeably with another drug that has fewer side effects.

(1) Atarax (hydroxyzine) has good stabilizing and antihistamine effects and has relatively few side effects.

(2) Epinephrine and aminophylline can increase CAMP in mast cells and inhibit the release of histamine, which has a good therapeutic effect on this disease.

(3) 6-Aminoacetic acid is also a good drug for cold urticaria.

(4) Calcium also has the effect of relieving symptoms of this disease.

3. Supplementing more vitamin C is an effective method that can cure this disease, and this method has also been clinically verified.

4. Topical application, calamine lotion or zinc oxide lotion can achieve temporary effects.