The efficacy and practice of Qianghuo
Notopterygium incisum, also known as Notopterygium incisum, alias Notopterygium, Messenger of the King of Hu, Notopterygium, Notopterygium, Black Medicine, Apiaceae, genus Notopterygium, perennial herb, height 60 -120 cm, the rhizome is thick and elongated in the shape of a bamboo. Below are the effects and methods of Qianghuo that I bring to you, welcome to read.
Effects of Qianghuo
It is used for symptoms of exogenous wind and cold, aversion to cold and fever, headache and body aches. This product has strong dispersing wind-cold and analgesic effects. It is often used with Fangfeng, Angelica dahurica and Asarum, such as Jiuwei Qianghuo Decoction.
It is especially suitable for pain in limbs and joints, shoulder and back pain caused by the invasion of wind, cold and dampness, especially pain in the upper body. This product can dispel wind, overcome temperature, dispel cold and relieve pain. Often used together with Fangfeng and Fangfeng, such as Juanbi Decoction.
Used for impotence and spermatorrhea, enuresis and frequent urination, cold pain in waist and knees, asthma due to kidney deficiency, and diarrhea at midnight; external use to treat vitiligo and alopecia areata. Relieves superficial cold, dispels wind and dampness, and relieves pain.
Relieves the appearance and dispels cold.
It is mainly used to treat wind-cold colds, aversion to cold, no sweating, headache and body aches.
Anti-allergic effect.
It has a certain inhibitory effect on delayed hypersensitivity in mice induced by 2,4-dinitrochlorobenzene (DNCB).
Antiarrhythmic effect.
Its water-soluble part can significantly shorten the duration of arrhythmia in rabbits and delay the onset of aconitine-induced arrhythmia in mice. This effect tends to increase with increasing dose, but when the dose increases When it reaches 12g/kg, its effect decreases.
Anti-myocardial ischemia effect.
Its volatile oil can resist acute myocardial ischemia caused by pituitary hormone. In addition, Qianghuo volatile oil can significantly increase myocardial nutritional blood flow, thereby improving myocardial ischemia.
Anti-shock effect.
It requires multiple administrations of small doses to be effective, but administration of a large dose at one time cannot improve the animal's anti-shock ability.
Anti-thrombotic, antioxidant.
Taking Qianghuo can prevent the formation of thrombosis. It has anti-lipid peroxidation effect.
Other functions.
Qianghuo also has anti-epileptic effects; it also has a certain inhibitory effect on cervical cells.
Pharmacological effects
(1) Antipyretic and analgesic.
Its volatile oil can significantly reduce the body temperature of experimentally febrile rats and has obvious analgesic effects. The aqueous extract of Qianghuoshengshi Decoction has obvious antipyretic and analgesic effects on rabbits with fever.
(2) Anti-inflammatory.
Its volatile oil has a significant inhibitory effect on the swelling of the soles of rats and the swelling of the auricles of mice when administered into the stomach. It can also significantly reduce the permeability of abdominal capillaries and reduce inflammatory exudation. Qianghuoshengshi Decoction has a strong anti-inflammatory effect. Its aqueous extract can significantly inhibit the hyperpermeability of abdominal capillaries and significantly inhibit inflammatory reactions such as swelling of the soles of rats and swelling of the auricles of mice. It showed a significant inhibitory effect on early joint swelling in adjuvant-type rats.
(3) Immunity.
It has a significant inhibitory effect on delayed-type hypersensitivity reactions; it can also significantly enhance the immune function of rat arthritis models, promote the phagocytosis of rat whole blood leukocytes, and increase the transformation rate of peripheral blood lymphocytes.
(4) Anti-arrhythmia and protection against myocardial ischemia.
Its aqueous extract can delay the onset of aconitine-induced arrhythmia in mice and significantly shorten the duration of the arrhythmia. Qianghuo volatile oil can resist acute myocardial ischemia caused by pituitaryin. This may be the result of dilation of the coronary arteries and increased coronary blood flow. Qianghuo volatile oil can significantly increase myocardial nutritional blood flow, thereby improving myocardial ischemia.
(5) Others.
Viscosity reduction: Its aqueous extract can significantly reduce the blood viscosity of rats.
Antibacterial: In in vitro tests, Qianghuo volatile oil has varying degrees of antibacterial effects on a variety of bacteria.
Efficacy of Qianghuo
Nature and flavor are bitter and warm.
"Decoction and Materia Medica": "The Qi is slightly warm, tastes bitter and sweet, and is flat."
Returns to the bladder and kidney meridian.
"Pearl Bag": "Foot Taiyang Bladder Meridian." "Hand Taiyang Small Intestine."
"Decoction Materia Medica": "Foot Taiyang, Jueyin Meridian."
"Materia Medica Mengquan": "Hand and foot Taiyang, foot Shaoyin and Jueyin meridians."
Functions: Dispersing superficial cold, dispelling rheumatism, and benefiting the joints. Cure colds and wind-colds, headaches without sweating, wind-cold and dampness-induced paralysis, strong tendons in the neck, sore joints, feng shui edema, and carbuncles and sores.
"Treatise on the Properties of Medicine": "Cure wind, aphasia, muteness, itching, bloody skin, paralysis of the hands and feet, abnormal mouth and face, and stubborn numbness all over the body."
"Rihua" "Zi Materia Medica": "Cure all wind and qi, spasm of muscles and bones, weakness of limbs, swollen head, sore eyes, redness and water qi, five kinds of fatigue and seven injuries, deficiency of cold air, sore joints, and tonifying the five internal organs."
"Pearl Sac": "Taiyang meridian relieves headaches, relieves joint pain, and can also warm the gallbladder."
"Pinhui Jingyao": "It mainly treats pain in hundreds of joints throughout the body, and on the muscle surface. The eight winds and evil spirits can remove old and new rheumatism, expel slough and ulcers."
"Compendium of Materia Medica": "Relax liver qi, search for liver wind, and treat rheumatism and rheumatism, headaches in this meridian (taiyang), and Du vessel. The disease is characterized by strong and weak spine, stiffness and tenderness, speechlessness, head spinning and red eyes. "Huiyue Medical Mirror": "Cure evil, aversion to cold, strong heat and no sweating."
Qianghuo attached prescription
To treat colds, fever and tonsillitis: Qianghuo 4 to 5 qian, isatis root and dandelion each one or two. Decoction in water, take one dose per day, divided into two doses. (Longhua Hospital Affiliated to Shanghai College of Traditional Chinese Medicine)
To treat Taiyang typhoid without sweating: Qianghuo, Duhuo, Schizonepeta, Fangfeng, Guangpi, and Licorice. Decoct and take. ("Medical Grade" Qianghuo Decoction)
To relieve teeth and colds: Qianghuo, Fangfeng, Atractylodes, Asarum, Chuanxiong, Angelica dahurica, Rehmannia glutinosa, Scutellaria baicalensis, and licorice. Take it decoction in water. If you take it with acute sweating and heat, take it with soup and porridge. If you take it with warm water to relieve sweating, do not take it with soup. (Zhang Yuuwei Jiuwei Qianghuo Decoction)
To treat headaches in the Taiyang Meridian: two points of Fangfeng, three parts of Qianghuo, and two red beans. At the end of the period, there is twitching in the nose. ("Jade Ji Weiyi")
To treat the symptoms of cold in the brain, brain pain with teeth, cold hands and feet, and cold breath in the mouth and nose: one penny of Qianghuo, five points each of aconite root and dried ginger, roasted Eight points of licorice. Decoction in water. ("Medical Enlightenment" Qianghuo Aconite Decoction)
To treat rheumatism, body aches, pain, inability to bend or stretch, or slight swelling of the body: Qianghuo (reed removed), aconite (cannon, peeled umbilicus) ), Atractylodes macrocephala, licorice (broiled) in equal parts. Take four qian each time, one and a half cup of water, five slices of ginger, fry until seven minutes, remove the phlegm, take it warm and at any time. ("Jisheng Prescription" Qiangfu Decoction)
To treat shoulder and back pain that cannot be recalled, spinal pain with strong neck, waist that seems to be broken, and neck that seems to be pulled out: Qianghuo and Duhuo each have one qian, Ligusticum root: Fangfeng, Licorice (broiled) and Ligusticum chuanxiong each have 5 points, and Vitex japonica has 3 points. Take one serving, two cups of water, boil one cup, remove the residue, take it warm, before eating. ("Differentiation of Internal and External Injuries" Qianghuo Shengshi Decoction)
Treatment of tonsillitis: 12-15g of Qianghuo, 30g each of Radix isatidis and Dandelion, decocted in water, 1 dose per day, divided into 2 doses. (Page 1173 of "Dictionary of Chinese Medicine") 9 Treatment of premature beats: "Pulse Qi" is an extract preparation of Qianghuo (provided by the China Academy of Traditional Chinese Medicine and produced by Guangzhou Xingqun Pharmaceutical Factory, 1ml pulse solution is equivalent to 1g of Qianghuo raw medicine), each 60-150ml daily, divided into 3-4 times, and the course of treatment is 7-14 days. ("Chinese Journal of Internal Medicine", 1985; 27(7): 452)
Side effects of Qianghuo
(1) Traditional literature
"Treatise on the Properties of Medicine": Non-toxic.
(2) Modern research
Chemical composition: This product contains volatile oil, β-sitosterol, coumarin compounds, phenolic compounds, carotene, and parsley B , organic acids and alkaloids, etc.
Pharmacological effects: Qianghuo injection has analgesic and antipyretic effects, and has inhibitory effects on dermatophytes and Brucella bacteria. The water-soluble part of Qianghuo has anti-experimental arrhythmia effects. Volatile oil also has anti-inflammatory, analgesic, and antipyretic effects, and can counteract myocardial ischemia caused by vasopressin and increase myocardial nutritional blood flow. It has an inhibitory effect on delayed allergic reactions in mice.
(3) Toxicology test
LD50: The LD50 of Qianghuo volatile oil administered to mice is 6.64g±0.87ml/kg.
Toxic reactions:
The maximum tolerated dose of Qianghuo aqueous extract by oral administration to mice is 40g (crude drug)/kg, and the maximum tolerated dose by intraperitoneal injection is 12.5g/kg kg.
The maximum tolerated dose of Qianghuoshengshi Decoction given to mice by intragastric administration is 62.4g (crude drug)/kg, which is equivalent to 133 times the clinical dosage.
In the long-term toxicity test of Qianghuoshengshi Decoction, rats were administered 46.80g/kg, 23.40g/kg, and 2.34g/kg (equivalent to 100, 50, and 5 times the clinical dosage.), continuously. After 4 weeks of administration and 2 weeks of drug withdrawal, no abnormal changes were found in the growth and development, blood routine, liver and kidney functions and important organs of the rats in each dose group.
The above shows that the toxicity of Qianghuo and Qianghuo Shengshi Decoction is very low and very safe.
(4) Clinical observation
Qianghuo is non-toxic. There is no discomfort when taken as a decoction in water within the normal dosage. There are no obvious side effects when taking it for a long time or taking it in large doses (less than 30g) by decoction in water.
Use 30g of water for each dose. Patients with arthritis generally have no obvious discomfort reaction, but some patients have reactions such as getting angry and sweating. For patients with colds and fever, it can induce sweating and reduce fever, but it does not increase internal heat; for people with original internal heat and spontaneous sweating due to physical weakness, 12g of water decoction will cause internal heat and increase sweating. This is what Chinese medicine says when there is a disease, the patient will suffer from it. The principle that if there is no disease, it will damage the righteousness.
Comprehensive recipe of Qianghuo
Qianghuo Fangfeng Decoction
The drug composition is 3 liang of Qianghuo (reed head removed), 4 liang of Fangfeng (with forks removed), and 3 liang of Platycodon grandiflorum. , Bupleurum (remove seedlings) 1 and a half, 3 taels of beijiang, Gui (remove rough skin) 1 and a half, rhubarb (file) 2 taels, antelope horn (pound crumbs) 1 tael.
The prescription comes from Volume 161 of "Sheng Ji Zong Lu".
The prescription is mainly used to treat postpartum abdominal hardness, fullness and distension of the flanks, cold hands and feet, restless heat in the heart, drinking and retching, and joint spasm and stroke.
According to the preparation method, it is crude powder.
Usage and Dosage: Take 5 qian dagger each time with 2 cups of water, decoct to 1 cup, remove the water, take it warmly on an empty stomach, and then take it again.
Qianghuo Atractylodes Decoction
The drug composition is 5 points of Zhigancao, 5 points of Phellodendron, 5 points of cardamom, 5 points of raw licorice, 5 points of Pueraria, 6 points of orange peel, 7 points of Bupleurum. Half, Cimicifuga 1 cent, Duhuo 1 cent, Amomum villosum 1 cent, Atractylodes 1 cent, Fangfeng 1 cent and 5 cents, Astragalus 2 cents, Anemarrhena 2 cents and 5 cents, Qianghuo 3 cents.
The prescription comes from the volume "Lanshi Secret Treasures".
The prescription is mainly used to treat weak and heavy feet and knees.
Usage and dosage: Take it by mouth. Divide into 2 servings, add 2 large cups of water, decoct to 1 cup, remove the dross, and take empty stomach.
Qianghuo Deshi Decoction
Source: "Collection of Medical Prescriptions".
To form the Qianghuoshengshi decoction, remove Duhuo, Sibiricus, Ligusticum chuanxiong, and licorice, and add Cimicifuga and Atractylodes.
It mainly treats rheumatism and rheumatism, which causes pain all over the body.
Qianghuo Fuzi Decoction
The prescription is 0.9g of ephedra (without removing the roots and joints) 0.9g of black aconite, 1.5g of Qianghuo, 1.5g of Atractylodes, 0.6g of Fangfeng, 3g of Astragalus, Licorice, Cimicifuga, 0.6g, Angelica dahuricae, White Bombyx, and Cortex Phellodendron, 0.9g each.
Function: Indications: The severe cold in winter affects the brain, causing brain pain and toothache, which is called cerebral wind.
Usage and Dosage: Take one dose. Add 300 ml of water, decoct to 150 ml, drain, and take warm after eating.
For cold cough, add 0.9 grams of Fructus Herba.
Excerpt from Volume 5 of "Dongyuan Trial Prescriptions"
Qianghuo Liquor
Source "Taiping Shenghui Prescription"
Formula Qianghuo I Two halves, one tael of Fangfeng (with reed heads removed), and one ounce of black beans for each serving.
In the preparation method of all the medicines, the first two ingredients are pounded into coarse rhizome and made into powder, soaked with five liters of good wine for one night.
It is mainly used to treat apoplexy, tremor, stiffness and opisthotonia of the limbs during pregnancy.
Usage: For each dose, stir-fry black beans to make the smoke come out, add the medicine, a large cup of wine, wait until it boils, remove the water, open the mouth, and pour it in two portions.
The difference between Qianghuo and Duhuo
"Shen Nong's Materia Medica" records that "Duhuo is called Qianghuo". "Compendium of Materia Medica" records that "Duhuo and Qianghuo are two species in one category." Therefore, the two books only have an entry on Duhuo and not on Qianghuo. Although the prescriptions of the Jin and Yuan Dynasties, such as Qianghuo Shengshi Decoction and Daqin Genji Decoction, contain both Qianghuo and Duhuo, herbalists still insist that they are the same medicine. This may be because they are plants of the same family and genus, and the shapes of their above-ground herbaceous parts are very similar. However, "Compendium of Materia Medica" has recognized that the two drugs "have different shapes, colors, and smells, so they are different theories."
The division of Qianghuo and Duhuo from one kind of medicine into two kinds of medicine shows that the understanding of traditional Chinese medicine is constantly being revised and gradually deepened, and it is constantly developing. Although it is slow, the attitude towards understanding is rigorous and scientific.
After Qianghuo and Duhuo were divided into two medicines, the saying that Qiang was superior and Duhuo was inferior appeared again. Is independent living only suitable for people below the waist? This is also a biased view.