How to tactfully refuse nicknames given by bosses and colleagues that only include your last name in the workplace?

You can jokingly tell them that this kind of nickname is really disgusting and don’t call them that again. If they always call it that way, you can say that you have said it too many times and they are You will definitely know that you are serious, so they will probably stop calling you that in the future. Some things must be said. If you don't say them, they will continue to be like this, so you need to speak bravely.