Will Genting s6.5 Lao Ba lose large sections?

Yes.

The top four players in Teamfight Tactics can gain points, while those ranked fifth and on will have their points deducted. If you lose too many points, you will lose your rank. If the number of victory points added by the player reaches the upper limit, the remaining victory points will be added directly after rising to the rank. For example, 93 points before the game, and 20 victory points after the game, will advance and become 13 victory points.