China Naming Network - Auspicious day query - Why is there a long COVID-19?

Why is there a long COVID-19?

There is a very common phenomenon: even after it turns cloudy, it is still weak, light-footed and very easy to get tired.

In fact, everyone is more worried about: how long will this fatigue and other symptoms last after "yang"? In other words, what people are more afraid of is the sequela of COVID-19.

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Long new crown, what is it?

The sequela of COVID-19 should be more accurately described as "acute sequela of COVID-19", "post-COVID-19 symptoms", "chronic COVID-19 syndrome" or "long coronavirus pneumonia".

At present, the World Health Organization (WHO) defines "long new crown" as: symptoms still exist for at least two months after being infected with COVID-19 virus for three months, and cannot be explained by other diagnoses; The most common are fatigue, shortness of breath and sleep disorder or insomnia.

Therefore, the cough, fatigue, shortness of breath and other feelings experienced by most "Yangkang" cannot be called COVID-19, but only the normal recovery period (even the acute period after infection).

What is the proportion of new crowns?

A study published by JAMA, a top medical journal, was led by WHO and completed by scientists from all over the world. It collected 54 studies and 2 medical databases, covering the data of 654.38+200,000 infected people in COVID-19.

The results showed that 6.2% people still had at least one symptom after being infected with COVID-19 virus for 3 months. After the infection of 1 year, 0.9% is still experiencing the sequelae of COVID-19.

The most common symptoms of long new crowns include three types:

① About 3.2% have persistent fatigue, accompanied by physical pain or mood swings;

② 3.7% of them have persistent respiratory problems, and the main symptoms are shortness of breath and persistent cough;

③ Among them, 2.2% have cognitive problems, forgetfulness or difficulty in concentration, which is the "brain fog" that is often heard recently.

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Proportion of long and new crowns (doi:10.1001/JAMA.1891)

This data based on early strains shows that 6.2% of COVID-19 infected people will experience a COVID-19; In Omicron, the probability of getting COVID-19 will be reduced by 0.24-0.50 (depending on the inoculation time of the last vaccine).

6.2%, even in Omicron, the probability of obtaining COVID-19 is 3. 1-4.7%, which is not high but not low.

Based on the "positive" calculation of 6.5438+0.2 million in this study, the "positive" of 37,000-56,000 will have COVID-19, especially among the people infected with COVID-19 today, everyone seems to be "opening the blind box", and it is impossible to predict whether this will happen after three months of infection.

However, eClinicalMedicine, a sub-journal of The Lancet, published a systematic review and meta-analysis on the concept of normality on June 5438+February 1, covering 194 studies with 735006 participants, revealing the "shocking" elements:

Whether hospitalized or not, at least 45% of COVID-19 infected people still have one or more symptoms within 4 months (average 126 days); The five most common symptoms are fatigue (28.4%), pain/discomfort (27.9%), sleep disorder (23.5%), dyspnea (22.6%) and limited activity (22.3%).

Even among non-hospitalized people, the most common symptom of COVID-19 is fatigue, which is as high as 34.8%(95%CI 17.6%-57.2%, 12 study)!

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Proportion of symptoms of new crown in non-hospitalized population

Of course, little is known about the strain of Chinese people and the growth of COVID-19 at present, but the above two reviews also suggest that we should not underestimate the growth of COVID-19, especially the persistent physical fatigue.

Attachment: "Long new crown" usually refers to the sequela of COVID-19. The World Health Organization calls it "post-COVID-19 symptoms", which refers to a series of long-term symptoms that some people experience after being infected with COVID-19 virus. Scholars use "post-COVID-19 syndrome" to describe the sequelae of COVID-19. Although the name is different, it has two main meanings: one is that the disease occurred after the acute infection period in COVID-19, and the other is that it contains many symptoms.