Sulfopyridine sulfasalazine suppository

[Product name and structure]

Official name: sulfasalazine suppository

English name: Sulfasalazine suppository

Chemical structural formula: The main component of this product is sulfasalazine, and its chemical name is 5-[ p -(2- pyridinesulfonyl)].

Benzazo salicylic acid, the chemical structural formula is as follows:

This product is a yellow or brownish yellow suppository, which is made of fat matrix.

[Pharmacology] Anti-inflammatory drugs. Anal suppository was given in the pharmacological experiment of rat immune ulcerative colitis model.

Through the comparative observation of the curative effect of oral drugs and tablets on colitis, it shows that anal suppository is effective.

Obviously superior to oral administration.

【 Absorption, distribution and elimination 】 This product enters the intestine and is decomposed into sulfapyridine and 5-aminosalicylic acid by intestinal bacteria.

5-aminosalicylic acid is eventually excreted through feces. Sulfopyridine can be absorbed into the blood and eventually excreted through urine. In the snow

In addition to the prototype of the product and sulfapyridine, there are acetylides and glucuronic acid conjugates in the solution.

Sulfopyridine and its acetylated products can be excreted with urine.

[Indications] Sulfonamides. Used for ulcerative colitis, nonspecific chronic colitis, etc.

【 Usage and Dosage 】 Severe patients should take one anal suppository each day after defecation in the morning, middle and evening. Moderate or mild patients sooner or later.

After defecation, use one anal suppository each. After the symptoms are obviously improved, switch to maintenance dose and use anal suppository once every night or every other night.

It is best to give the medicine at intervals before going to bed.

[Adverse reactions] The maximum daily dosage of this product for adults is 1.5g, and no obvious adverse reactions have been found in clinical application.

[Precautions] 1, which is prohibited for those who are allergic to sulfonamides. 2. Sometimes the surface of the plug is analyzed when placing the product.

Bleeding is caused by matrix, which is a normal phenomenon and does not affect the curative effect.

[Specification] 0.5g/ capsule

"Packaging" 6 capsules/box

[Storage] Keep away from light, sealed and stored below 30℃.

[service life] three years

[Approval number] National Medicine Zhunzi H 1090009 1

[Manufacturer] Shanxi Sanjiu Tongda Pharmaceutical Co., Ltd.

[Address] No.57 Xinjian South Road, Datong City, Shanxi Province

[Postal] 037000

[Tel] 0352-5036999

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